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br Role of dysfunctional telomeres in activation of p MAPK
2019-04-25
Role of dysfunctional telomeres in activation of p38 MAPK pathway as response to genotoxic stress Telomeres are unique structures at the ends of chromosomes that are located adjacent to more gene rich sub-telomeric regions and comprised of tandem GT-rich repeats, (TTAGGG)n in humans and other ver
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Dyslipidemia is characterized by increased total cholesterol
2019-04-25
Dyslipidemia is characterized by increased total cholesterol, LDL-C, and triglyceride levels, and decreased HDL-C levels. However, the association of ApoA1 polymorphism with serum HDL-C level remains controversial. The polymorphisms of ApoA1+84 TC, but not MspI, are associated with serum HDL-C. The
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br What is the best pacing algorithm for vasovagal
2019-04-25
What is the best pacing algorithm for vasovagal syncope? Conclusions Conflict of interest Introduction The number of implantations of cardiovascular implantable electronic devices (CIEDs), including permanent pacemakers (PPMs), implantable cardioverter defibrillators (ICDs), and cardiac
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Cholangiopathies are a group of rare
2019-04-25
Cholangiopathies are a group of rare diseases whose primary or secondary target is the cholangiocyte. The onset and subsequent development processes of cholangiopathies are extremely diverse, with causes that are genetic, neoplastic, immune-mediated, idiopathic, infectious, and toxin- or drug-induce
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br Imagine providing care for low birthweight LBW lighter
2019-04-25
Imagine providing care for 900 000 low birthweight (LBW; lighter than 2500 g) newborn babies each year in sub-Saharan Africa—all attributable to preventable and treatable malaria. Many of these LBW babies will be born in rural and impoverished settings where access to health care is poorest and th
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br Alegato y ret rica de
2019-04-25
Alegato y retórica de la violencia en la Brevíssima relación de la destruyción de las Indias En el año 1552 fray Bartolomé de las Casas, en Sevilla, se ocupa de dar regadenoson la imprenta ocho de sus principales escritos, entre ellos la Brevíssima relación, compuesta diez años antes: “Y pareciól
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Para el Movimiento Social Ind
2019-04-25
Para el Movimiento Social Indígena, el lugar de la protesta es su propio territorio ancestral que es defendido frente ARQ 621 los actores armados. Así, el lugar adquiere por lo menos tres características: a) como sitio donde se realiza la acción colectiva, b) como el motivo y causa de la acción cole
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purchase A 779 br CONSIDERACIONES FINALES Como se infiere de
2019-04-25
CONSIDERACIONES FINALES Como se infiere de los ejemplos revisados en el apartado anterior, podríamos decir que esta suerte de homenaje póstumo concretado en las notas necrológicas de la RF está destinado purchase A 779 figuras intelectuales que sintonizan con la orientación ideológica de la publi
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br Procedural endpoints The most commonly employed electroph
2019-04-24
Procedural endpoints The most commonly employed electrophysiological endpoint is the achievement of noninducibility. While noninducibility has been shown to be predictive for clinical freedom from recurrent VT, it has not been uniformly the case [1,2]. Inducibility of VT is probabilistic and rare
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br Discussion Prehabilitation is a program to enhance
2019-04-24
Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, an
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The exhibited efficacies of bone targeting treatments
2019-04-24
The exhibited efficacies of bone targeting treatments, in phase III clinical trials, suggest significant progress in delaying skeletal-related events, with improvements having been seen in the direct comparisons between generations of drugs. These findings also lend clear support to the utility of b
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Primary lymphoma of bone is
2019-04-24
Primary lymphoma of bone is an uncommon clinical entity and accounts for less than 5% of malignant bone tumors, 4–5% of extra nodal lymphoma and less than 1% of all non-Hodgkin\'s lymphoma. Diffuse large-B-cell lymphoma (DLBCL) accounts for the majority of cases of PBL [2]. The varied clinical and
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br Predictors of benefit from bisphosphonates Randomized con
2019-04-24
Predictors of benefit from bisphosphonates Randomized control studies of adjuvant BP therapy in early breast cancer show benefit related to “low estrogen states” [1,2,5,6]. Unfortunately, thus far, only one study has assessed systemic estrogen levels to substantiate these results. This is clearly
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Since BM impairs the balance between bone
2019-04-24
Since BM impairs the balance between bone formation and bone resorption, altered bone remodeling activities can be assessed directly by measuring the components of affected bone cells or indirectly by analyzing metabolic products released from the bone matrix by changed rates of bone formation or re
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An enhanced T wave suppression mode
2019-04-24
An enhanced T wave suppression mode was very effective to manage TWOS and was able to detect induced and spontaneous VF correctly. On the other hand, it has been reported that Biotronik devices connected to integrated bipolar ICD leads from other manufacturers had an increased risk for oversensing [
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