• The apocrine sweat glands of the human axilla

  2025-02-12

  

  The apocrine sweat glands of the human axilla produce odor substances with pheromone functions whose nature corresponds to volatile steroids (Cowley and Brooksbank, 1991, Grosser et al., 2000, Sobel et al., 1999, Weller, 1998). These functions only begin with puberty, indicating that sex hormones st

• Asparagine synthetase ASNS is a

  2025-02-12

  

  Asparagine synthetase (ASNS) is a glutamine amidotransferase that catalyzes ATP-dependent synthesis of asparagine and glutamate from aspartate and glutamine. Upregulation of ASNS expression renders leukemia cells resistant to l-asparaginase treatment, and ASNS is essential for cell survival in the a

• br Methods br Results br Discussion By following a

  2025-02-12

  

  Methods Results Discussion By following a large cohort of older persons for up to 11 years, we found that subjects with more degraded FR in motor activity (i.e., weaker temporal activity correlations at time scales  predict incident AD dementia and MCI risk is independent of many other AD r

• br Materials and methods br Results br Discussion

  2025-02-12

  

  Materials and methods Results Discussion Knowledge of the molecular basis of an inherited genetic disease is crucial for understanding the disease pathology and, ultimately, for therapeutic design. Several recent reports have stressed the need for physical characterization of disease-associ

• Polyphyllin VII Blocking the action of CREB with the C

  2025-02-12

  

  Blocking the action of CREB with the C646 inhibitor together with increasing Akt activation with the SC79 agonist is particularly interesting as it significantly reduced wound closure time from 7 days (which is required for complete closure of control hTECs exposed to DMSO) to only 4 days (when hTEC

• The difference in the mean values of serum ADA

  2025-02-12

  

  The difference in the mean values of serum ADA in sputum positive PTB and controls was found to be highly significant (P Discussion Tuberculosis is a major health problem in India, and out of all its forms PTB is the commonest. A definite diagnosis of PTB can be made with the presence of baclofen

• br Results br Discussion To achieve

  2025-02-12

  

  Results Discussion To achieve quantitative understanding of MTEP hydrochloride synthesis turnover, we utilize rapidly moving lamellipodial fragments that are geometrically simple, structurally homogeneous, and persistent, and measure relevant rates and concentrations in this system. We find t

• The AChR is composed of five homologous membrane spanning su

  2025-02-12

  

  The AChR is composed of five homologous, membrane-spanning subunits. AChRs containing two α, one β, one δ and one γ subunit (AChRγ) predominate during embryonic development and mice lacking AChRγ die at birth (Takahashi et al., 2002). After birth, the AChRγs are replaced during the first 2 postnatal

• Owing to efficient catalytic character high

  2025-02-12

  

  Owing to efficient catalytic character, high electrolyte accessible area, easy fabrication and many other interesting properties, metal oxide nanoparticles are extensively used in a variety of electro-analytical processes [14]. Metal oxide nanoparticles immobilized over a conductive and large area s

• The H N mutation in exon has not

  2025-02-11

  

  The H373N mutation in exon 6 has not previously been reported [3], [4], [5], [6]; thus, this mutation appears to be a novel mutation. The functional expression study demonstrated that the H373N mutation results in almost complete loss of enzymatic activity. Thus, it is highly likely that the H373N m

• As mentioned above variation of the

  2025-02-11

  

  As mentioned above, variation of the A-ring was undertaken in order to improve microsomal stability and kinase selectivity relative to gaba receptor (). 1-Imidazole-2-carboxamides with substitution at the 4-position (–) were mostly tolerated with 4-cyano-imidazole-2-carboxamide () having comparable

• Autophagy is a highly conservative

  2025-02-11

  

  Autophagy is a highly conservative intracellular bulk degradation process including three major forms namely microautophagy, chaperone-mediated autophagy and macroautophagy. A large number of evidence has depicted a pivotal role for autophagy in the maintenance of cardiac geometry and contractile fu

• In liver the essential organ

  2025-02-11

  

  In liver, the essential organ of lipoprotein synthesis, ACL plays a fundamental role in lipogenesis and steroidogenesis by supplying cytosolic chlorpheniramine maleate with dextromethorphan hydrobromide syrup to both pathways. By using a tricarboxylic acid cycle intermediate (citrate) to produce ac

• sesamin It is increasingly evident that many metabolic genes

  2025-02-11

  

  It is increasingly evident that many metabolic genes are associated with cancer progression of various tumor cells, including NSCLC. In particular, GLUT1 overexpression has been reported in NSCLC, and correlations between GLUT1 expression and a number of clinical parameters such as gender, smoking s

• In the case of DIA CN the docking results do

  2025-02-11

  

  In the case of DIA-4CN the docking results do not show any interaction between the iron atom and the inhibitor, presumably due to the reduced ability to form a complex involving the -CONN- moiety versus the bidentate -CONHNH- central group of HYD-4Me. This results in a considerable gap between the i

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