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In Antirrhinum floral organ identity genes include DEFICIENS
2023-07-19
In Antirrhinum, floral organ identity genes include DEFICIENS (DEF) (Sommer et al., 1990) and GLOBOSA (GLO) (Trobner et al., 1992) required for petal and stamen identity (B-function), PLENA (P) required for stamen and carpel formation (C-function) (Bradley et al., 1993) and SQUAMOSA (SQUA) which is
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Optical coherence tomography angiography is another promisin
2023-07-19
Optical coherence tomography angiography is another promising method for the assessment of corneal neovascularization. This relatively new modality is not yet widely used in part because of current limitations in the definition of images produced, lack of functional information, and inability to det
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Thalidomide is now a well known antiangiogenic agent
2023-07-19
Thalidomide is now a well known antiangiogenic agent. This property of thalidomide is being extensively researched upon, for its significant utility in the treatment of various malignant tumors. Studies show that thalidomide efficaciously inhibits various pro-angiogenic factors such as tumor necrosi
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In our study we provide evidence for the existence of
2023-07-19
In our study we provide evidence for the existence of an endosome-lysosomal pathway for the proteolytic degradation of AR triggered by its interaction with the ESCRT-I component TSG101. The following findings of this study support this notion: (1) We showed that TS101 interacts with endogenous or ec
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Intracellular Signaling Cascades From ligand
2023-07-19
Intracellular Signaling Cascades. From ligand sensitization to translation of genes, all cellular processes are dependent on the intracellular levels and activity of partners involved in the signaling pathway. These signaling events lead to critical post-translational modifications including phospho
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Although mature fibrils formed from A aggregates have long b
2023-07-19
Although mature fibrils formed from Aβ Oxaliplatin have long been thought to be the main neurodegenerative agents in AD, recent evidence suggests that soluble multimers of these pathogenic proteins, referred to here as “oligomers,” may initiate the synaptic and neuronal dysfunction associated with
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The rescue of the behavioral deficit
2023-07-19
The rescue of the behavioral deficit was associated with a significant reduction in the levels of both soluble and insoluble Aβ peptides and their deposition in the (-)-p-Bromotetramisole Oxalate synthesis of the same animals. In search for the mechanism behind the reduced amyloidosis, we assessed
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br Materials and Methods br
2023-07-18
Materials and Methods Results In the Base Analysis (53% of patients having access to the ALK test in both Current and Alternative Scenarios), a total of 16,583 patients were tested of whom 1,252 were assumed to be ALK-positive. A more extensive use of Ventana in the Alternative Scenario determ
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Synthesis of the pterin carboxamides was achieved
2023-07-18
Synthesis of the pterin-7-carboxamides was achieved, as shown in , based on a previously reported method that utilizes DBU as a key additive to dissolve pterin in organic solvents and accelerate the reaction., With this method, the pterin-amino LY2606368 HCl conjugates (–) were readily obtained by s
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Rising depolarization was observed during
2023-07-18
Rising depolarization was observed during and decaying depolarization after the photostimulation (Fig. 1D). The slow decrease of the firing rate after photostimulation is also a remarkable characteristic of the striatal neuron (Figs. 1E, 2 and 3), since the cortex pyramidal neurons (data not shown)
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It is worth mentioning that cordycepin
2023-07-18
It is worth mentioning that cordycepin, as an adenosine analogue, is structurally similar to adenosine. A previous study has shown that the anti-apoptotic effects of cordycepin are partially dependent on the activation of A1R [16], and cordycepin increases theta waves power density via nonspecific a
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PL for actin in vitro
2023-07-18
PL for Estradiol 17-(β-D-Glucuronide) sodium salt in vitro showed that its profiles, including particular peak and intensity, could determine the length and thickness of an actin filament. Furthermore, we investigated if the PL intensity peak at approximately 340 nm can also be originated from anot
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Evaluation of plant growth Transgenic Arabidopsis plants wer
2023-07-18
Evaluation of plant growth. Transgenic Arabidopsis plants were examined by microscope for alterations in cell size and shape. Overall plant architecture was also compared with control plants. Results and discussion Acknowledgments Introduction Mammalian ACK1 is a kinase effector for Cdc42
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There has been growing interest over computational methods t
2023-07-18
There has been growing interest over computational methods to predict the biological activity by chemical structure, so as to decide whether it Pregnenolone Carbonitrile has objective qualities or not. In this contribution, the well-known method, which is called quantitative structure–activity relat
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br Conclusions br Conflicts of interest br Acknowledgements
2023-07-18
Conclusions Conflicts of interest Acknowledgements This work was supported by Ege University Research Fund [BAP, 14-ECZ-030, 2016]. Introduction The interest in the effects of endocrine disrupting chemicals (EDCs) in the aquatic environment continues to increase over the past decade, sp
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