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STF-62247 Some studies have integrated the use of cloud
2020-09-03
Some studies have integrated the use of cloud computing with user interfaces in the domain of our proposal (i.e. UI). In [24] the authors work with Android devices to achieve more flexibility in the user interfaces by making use of information about the environment (for example, with an ambient ligh
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Mitomycin C The serotonin transporter gene encodes an integr
2020-09-03
The serotonin transporter gene () encodes an integral membrane protein that transports serotonin from the synaptic spaces into the presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent way. This protein is a target of psychomotor stimulants
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Organ fibrosis is thought to be initiated
2020-09-03
Organ fibrosis is thought to be initiated by repeated or chronic epithelial injury. The current belief is that damaged epithelial STAT5 Inhibitor induce an aberrant and unresolved wound repair process by activating fibroblasts via various profibrotic cues. Upon injury, epithelial cells activate the
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br Ultrasonic pretreatment of substrates Substrate pretreatm
2020-09-03
Ultrasonic pretreatment of substrates Substrate pretreatment is widely used in the biofuel, textile and food industries since the substrates are always difficult to degrade. During some enzymatic hydrolysis reactions, the protective layer of the substrate impedes the reaction. Ultrasonic treatmen
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In addition to EGFR other receptor tyrosine kinases RTKs als
2020-09-03
In addition to EGFR, other receptor tyrosine kinases (RTKs) also play roles in the tumor progression under hypoxia, especially hepatocyte growth factor receptor (cMet) (Le et al., 2012). Our data suggested that unlike EGFR, hypoxia had no apparent effect on cMet hyPerFUsion™ high-fidelity PCR Kit (d
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br Methods br Results br Discussion Skin
2020-09-03
Methods Results Discussion Skin biopsy and microneurography have both been described as useful tools in the diagnosis of PAN, directly identifying peripheral sympathetic fibers without the mediation of specific Sweroside australia organs (Donadio et al., 2005, Donadio et al., 2012a, Donadi
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To determine whether the same concentration of
2020-09-03
To determine whether the same concentration of humic Nitrotetrazolium Blue chloride causes changes in PCR efficiency, we performed another experiment in which the humic acid was added to the PCR mix after bisulfite conversion. All samples that were amplified in the presence of humic acid (thick lin
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Previously we showed that MS a combined extract of
2020-09-02
Previously, we showed that MS-10, a combined extract of Cirsium japonicum var. Maackii (Maxim.) Matsum. (Korean milk thistle) and Thymus vulgaris L., increases the efficiency of estrogen in the estrogen-deficient state by activating the estrogen receptor (ER). MS-10 increased bone mineral density (B
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br Competing interests br Acknowledgements br
2020-09-02
Competing interests Acknowledgements Introduction Diacylglycerol kinase (DGK) phosphorylates diacylglycerol (DG) in biomembranes to produce phosphatidic GSK2656157 (PA) [1], [2], [3], [4], [5], [6]. To date, ten mammalian DGK isozymes (α, β, γ, δ, ε, ζ, η, θ, ι and κ) have been identified.
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Three kinase inhibitors dasatinib type I imatinib type II
2020-09-02
Three kinase inhibitors dasatinib (type I), imatinib (type II) and nilotinib (type II), identified initially as inhibitors of tyrosine kinase BCR-ABL, were found to target DDRs in a chemical proteomic profiling study (Bantscheff et al., 2007, Hantschel et al., 2008). These tyrosine kinase inhibitors
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br Conflicts of interest br Acknowledgements This
2020-09-02
Conflicts of interest Acknowledgements This work was supported by the Swiss National Science Foundation No 31003A-179400 to AO. We thank Dr. Thierry Langer, University of Vienna and Inte:Ligand GmbH, for providing the LigandScout Software, and Dr. Daniela Schuster, Paracelsus Medical Universit
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Our observation that nuclear but not cytoplasmic EP expressi
2020-09-01
Our observation that nuclear, but not cytoplasmic EP4 expression is associated with different outcomes is interesting. In breast cancer, using the same methods, we did not detect EP4 in the nucleus of malignant Atovaquone whereas cytoplasmic EP4 was commonly observed [13]. While G protein-coupled r
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Enzyme mimics belong to a type of rising
2020-09-01
Enzyme mimics belong to a type of rising catalysts which show the similar function with their corresponding natural enzymes [20], [21], [22], [23], [24], [25], [26], [27], although their structures are different from natural enzymes. In the area of prodrug activation, the widely-used enzyme mimics a
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Interestingly ASV infusion in the dRN of saline pre
2020-09-01
Interestingly, ASV-30 infusion in the dRN of saline pre-treated rats had no effect on anxiety-like behaviors. This result may be due to the saline pre-treated group exhibiting relatively low levels of anxiety-like behaviors (when compared to saline pre-treated rat of the first experiment that were n
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The authors then showed that Spt interacts
2020-09-01
The authors then showed that Spt6 interacts directly with the PRC2 subunit Suz12. This interaction occurs in solution but not on chromatin, suggesting that Spt6 may prevent PRC2 recruitment by binding to Suz12. They then mapped the domains in both Spt6 and Suz12 that are involved in this interaction
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