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P falciparum DHFR TS is
2020-09-27
P. falciparum DHFR-TS is a particularly important enzyme, because it is from the protozoan species that is associated with most malaria infections. Since this enzyme is responsible for catalyzing sequential reactions in the thymidylate cycle, its inhibition slows malarial dTMP production and therefo
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The annotation is arguably the most important part
2020-09-27
The annotation is arguably the most important part of analysis, as it enables one to evaluate and interpret the content of the transcriptome assembly. In this context, the non-redundant contigs were initially run in BLAST against the Nr database showing that 55% of them displayed high similarity to
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Furthermore our sample preparation uses a simple
2020-09-27
Furthermore, our sample preparation uses a simple isolation procedure. Numerous CYP450 phenotyping methods employed extensive extraction procedures for sample preparation such as dual liquid extraction or solid phase extraction which are costly and time consuming [10], [17], [18], [19], [20], [23],
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Physiological changes induced by CRF are mediated through CR
2020-09-27
Physiological changes induced by CRF are mediated through CRF1 and CRF2 receptors (Chang et al., 1993, Lovenberg et al., 1995). Previous findings with CRF1 receptor antagonists showed that activation of CRF1 receptor is involved in maternal separation-induced ultrasonic vocalizations (Kehne et al.,
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Fig shows graphically the abundance distributions
2020-09-27
Fig. 3 shows, graphically, the abundance distributions of the ARD% of the investigated data with both the CPA-NRTL and CPA-UNIQUAC models, where ARD% is defined as,in which x and x are the experimental and calculated SO2 molar compositions in the liquid phase, respectively, and N is the total number
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During recent years two primary types of
2020-09-27
During recent years, two primary types of models have been applied for calculating various thermodynamic properties of amino ISRIB solutions, i.e. excess Gibbs energy (gE) models used numerously to describe the solubility of amino acid solutions, and equations of state (EOS) models appropriate to ob
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br Theory br Method To
2020-09-27
Theory Method To test our hypotheses as shown in Fig. 1, we conducted a survey at an international media company (hereafter referred to as ‘MediaCo’) headquartered in the UK. Its 5500 employees are dispersed throughout the world, partly due to massive acquisitions within the past decade. In ex
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Due to the results of the experiment we decided to
2020-09-27
Due to the results of the experiment we decided to deploy our cloud service infrastructure with two platform-independent servers instead of one or three. This decision was based on two factors: (a) the use of more than one server is useful to avoid a bottleneck in the system, and (b) using more than
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Antioxidants such as SFN have
2020-09-27
Antioxidants such as SFN have been proposed to be chemopreventive agents to inhibit, delay or reverse the development of cancer (Bayat Mokhtari et al., 2018). SFN was shown in breast epithelial cell culture to suppress oxidative metabolism of E2/E1 and thus protect against estrogen-mediated DNA dama
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br Acknowledgements br Introduction In
2020-09-27
Acknowledgements Introduction In Arabidopsis thaliana (L.) Heynh, there are at least four copies of the caseine kinase-like gene Ck1, which is involved in peptide phosphorylation in mammals [1]. These genes are distributed on LDN193189 1, 2, 4, and 5. A similar number of copies for Ck1 have b
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It is of interest to point out that curcumin in
2020-09-26
It is of interest to point out that curcumin in this study reduced body weight gain; the underlying mechanism may be due to a decrease in general N1-Methylguanosine-5\'-Triphosphate of fat, which was associated with a significantly reduced NPC1L1 expression in small intestine. Labonte et al reveale
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Material and Methods We reviewed
2020-09-25
Material and Methods We reviewed the following databases to obtain relevant studies of udenafil: PubMed, Embase, and the Cochrane Library. The following search terms were used: (“udenafil” OR “Zydena” OR “DA 8159”) AND (“Erectile Dysfunction” OR “Impotence”). We also searched the references of incl
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To provide a brief critical evaluation of this
2020-09-25
To provide a brief critical evaluation of this technology and an outlook, we note that performance of SMEPT is critically dependent on each of the components making up this platform, namely the substrate, the enzyme, and the prodrug. With regards to the latter, SMEPT is built on the experience and s
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To compare the phage of the th
2020-09-25
To compare the phage of the 4th round results, we conducted isolated single rounds of FGE screening as described above for the 4 individual phage 4(1), 4(2), 4(3), and NC then determined the number of colony forming units afforded by cleavage from the support. Interestingly, we found that the 4(2) s
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br Transparency document br Introduction Cigarette smoke
2020-09-25
Transparency document Introduction Cigarette smoke is modifiable factors to alter the neurovascular functions. Now a day, cigarette smoking in public place is offense due to toxic exposure cause the neurological and respiratory system damage to non-smoker population [1]. A literature survey ex
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